PTH-Vitamin D-Glycemia Interactions Reloaded
نویسندگان
چکیده
منابع مشابه
Paul Lee PTH - Vitamin D - Glycemia Interactions Reloaded
Traditionally viewed as a key regulator of musculoskeletal health, recent studies also have pointed to pleiotropic roles of vitamin D in the modulation of metabolic and vascular functions (1). Hypovitaminosis D is associated with obesity (2), and low vitamin D states predict higher fasting glycemia and insulin resistance in population studies (3,4), yet other studies showed no relations between...
متن کاملPTH Reloaded: A New Evolutionary Perspective
The parathyroid hormone (PTH) family is a group of structurally-related secreted peptides involved in bone mineral homeostasis and multitude of developmental processes in vertebrates. These peptides mediate actions through PTH receptors (PTHRs), which belong to the transmembrane G protein-coupled receptor group. To date, genes encoding for PTH and PTHR have only been identified in chordates, su...
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OBJECTIVE To assess the effect of timing of intraoperative parathormone (iPTH) samples and 25-hydroxyvitamin D (25-OHD) status on decision-making during parathyroidectomy. METHODS A total of 77 patients with primary hyperparathyroidism and iPTH levels (preincision, preremoval, 5 (T5) and 10 (T10) minutes postremoval) performed during parathyroidectomy were reviewed. RESULTS Forty-one percen...
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Acute administration of dihydroxycholecalciferol [1,25(OH)(2)D(3)] blunts phosphaturia and increases urinary cAMP excretion in parathyroid hormone (PTH)-infused parathyroidectomized (PTX) rats. Because chronic administration of 1,25(OH)(2)D(3) enhances the phosphaturic response to exogenous parathyroid hormone despite blunting of urinary cAMP excretion, we have examined the expression of the re...
متن کاملImpact of two regimens of vitamin D supplementation on calcium - vitamin D - PTH axis of schoolgirls of Delhi.
OBJECTIVE To determine the efficacy of supplementation with oral vitamin D₃ (cholecalciferol) on bone mineral biochemical parameters of school-going girls. SETTING Government school (government-aided) and Private school (fee paying) in Delhi. DESIGN Randomized controlled trial. INTERVENTION Cholecalciferol granules (60,000 IU) orally with water, either once in two months (two-monthly D₃ g...
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ژورنال
عنوان ژورنال: Diabetes
سال: 2014
ISSN: 0012-1797,1939-327X
DOI: 10.2337/db14-0956